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Myoblasts generated by lentiviral mediated MyoD transduction of myotonic dystrophy type 1 (DM1) fibroblasts can be used for assays of therapeutic molecules

BACKGROUND: Myotonic dystrophy type 1 (DM1) is the most common muscle dystrophy in adults. The disease is caused by a triplet expansion in the 3'end of the myotonic dystrophy protein kinase (DMPK) gene. In order to develop a human cell model for investigation of possible effects of antisense an...

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Detalles Bibliográficos
Autores principales:	Larsen, Jan, Pettersson, Olof J, Jakobsen, Maria, Thomsen, Rune, Pedersen, Christina B, Hertz, Jens M, Gregersen, Niels, Corydon, Thomas J, Jensen, Thomas G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226528/ https://www.ncbi.nlm.nih.gov/pubmed/22078098 http://dx.doi.org/10.1186/1756-0500-4-490

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