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A Quantitative Method for the Specific Assessment of Caspase-6 Activity in Cell Culture

Aberrant activation of caspase-6 has recently emerged as a major contributor to the pathogeneses of neurodegenerative disorders such as Alzheimer's and Huntington disease. Commercially available assays to measure caspase-6 activity commonly use the VEID peptide as a substrate. However these met...

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Detalles Bibliográficos
Autores principales: Ehrnhoefer, Dagmar E., Skotte, Niels H., Savill, Jane, Nguyen, Yen T. N., Ladha, Safia, Cao, Li-Ping, Dullaghan, Edie, Hayden, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226564/
https://www.ncbi.nlm.nih.gov/pubmed/22140457
http://dx.doi.org/10.1371/journal.pone.0027680