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Cholesterol Tuning of BK Ethanol Response Is Enantioselective, and Is a Function of Accompanying Lipids

In the search to uncover ethanol's molecular mechanisms, the calcium and voltage activated, large conductance potassium channel (BK) has emerged as an important molecule. We examine how cholesterol content in bilayers of 1,2-dioleoyl-3-phosphatidylethanolamine (DOPE)/sphingomyelin (SPM) and 1-p...

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Detalles Bibliográficos
Autores principales: Yuan, Chunbo, Chen, Maohui, Covey, Douglas F., Johnston, Linda J., Treistman, Steven N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226590/
https://www.ncbi.nlm.nih.gov/pubmed/22140451
http://dx.doi.org/10.1371/journal.pone.0027572