Deletion of Munc18-1 in 5-HT Neurons Results in Rapid Degeneration of the 5-HT System and Early Postnatal Lethality

The serotonin (5-HT) system densely innervates many brain areas and is important for proper brain development. To specifically ablate the 5-HT system we generated mutant mice carrying a floxed Munc18-1 gene and Cre recombinase driven by the 5-HT-specific serotonin reuptake transporter (SERT) promote...

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Detalles Bibliográficos
Autores principales: Dudok, Jacobus J., Groffen, Alexander J. A., Toonen, Ruud F. T., Verhage, Matthijs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226659/
https://www.ncbi.nlm.nih.gov/pubmed/22140524
http://dx.doi.org/10.1371/journal.pone.0028137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226659/
https://www.ncbi.nlm.nih.gov/pubmed/22140524
http://dx.doi.org/10.1371/journal.pone.0028137

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