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γ-Radiation Promotes Immunological Recognition of Cancer Cells through Increased Expression of Cancer-Testis Antigens In Vitro and In Vivo

BACKGROUND: γ-radiation is an effective treatment for cancer. There is evidence that radiotherapy supports tumor-specific immunity. It was described that irradiation induces de novo protein synthesis and enhances antigen presentation, we therefore investigated whether γ-radiation results in increase...

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Detalles Bibliográficos
Autores principales: Sharma, Anu, Bode, Beata, Wenger, Roland H., Lehmann, Kuno, Sartori, Alessandro A., Moch, Holger, Knuth, Alexander, von Boehmer, Lotta, van den Broek, Maries
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226680/
https://www.ncbi.nlm.nih.gov/pubmed/22140550
http://dx.doi.org/10.1371/journal.pone.0028217