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The core domain as the force sensor of the yeast mechanosensitive TRP channel

Stretch-activated conductances are commonly encountered in careful electric recordings. Those of known proteins (TRP, MscL, MscS, K(2p), Kv, etc.) all share a core, which houses the ion pathway and the gate, but no recognizable force-sensing domain. Like animal TRPs, the yeast TRPY1 is polymodal, ac...

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Detalles Bibliográficos
Autores principales: Su, Zhenwei, Anishkin, Andriy, Kung, Ching, Saimi, Yoshiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226973/
https://www.ncbi.nlm.nih.gov/pubmed/22124118
http://dx.doi.org/10.1085/jgp.201110693