Estimation of vaccine efficacy in a repeated measures study under heterogeneity of exposure or susceptibility to infection

Vaccine efficacy (VE) is commonly estimated through proportional hazards modelling of the time to first infection or disease, even when the event of interest can recur. These methods can result in biased estimates when VE is heterogeneous across levels of exposure and susceptibility in subjects. The...

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Detalles Bibliográficos
Autores principales: Valim, Clarissa, Mezzetti, Maura, Maguire, James, Urdaneta, Margarita, Wypij, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227149/
https://www.ncbi.nlm.nih.gov/pubmed/18407892
http://dx.doi.org/10.1098/rsta.2008.0044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227149/
https://www.ncbi.nlm.nih.gov/pubmed/18407892
http://dx.doi.org/10.1098/rsta.2008.0044

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