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Explaining the Structural Plasticity of α-Synuclein
[Image: see text] Given that α-synuclein has been implicated in the pathogenesis of several neurodegenerative disorders, deciphering the structure of this protein is of particular importance. While monomeric α-synuclein is disordered in solution, it can form aggregates rich in cross-β structure, rel...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227348/ https://www.ncbi.nlm.nih.gov/pubmed/22029383 http://dx.doi.org/10.1021/ja208657z |