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Copy-Number Variation: The Balance between Gene Dosage and Expression in Drosophila melanogaster

Copy-number variants (CNVs) reshape gene structure, modulate gene expression, and contribute to significant phenotypic variation. Previous studies have revealed CNV patterns in natural populations of Drosophila melanogaster and suggested that selection and mutational bias shape genomic patterns of C...

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Detalles Bibliográficos
Autores principales: Zhou, Jun, Lemos, Bernardo, Dopman, Erik B., Hartl, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227403/
https://www.ncbi.nlm.nih.gov/pubmed/21979154
http://dx.doi.org/10.1093/gbe/evr023