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Repairing split ends: SIRT6, mono-ADP ribosylation and DNA repair

The sirtuin gene family comprises an evolutionarily ancient set of NAD+ dependent protein deacetylase and mono-ADP ribosyltransferase enzymes. Found in all domains of life, sirtuins regulate a diverse array of biological processes, including DNA repair, gene silencing, apoptosis and metabolism. Stud...

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Detalles Bibliográficos
Autores principales: Van Meter, Michael, Mao, Zhiyong, Gorbunova, Vera, Seluanov, Andrei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227448/
https://www.ncbi.nlm.nih.gov/pubmed/21946623