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HIC-5: A Mobile Molecular Scaffold Regulating the Anchorage Dependence of Cell Growth
HIC-5 is a multidomain LIM protein homologous to paxillin that serves as a molecular scaffold at focal adhesions and in the nucleus. It forms mobile molecular units with LIM-only proteins, PINCH, and CRP2 and translocates in and out of the nucleus via a nuclear export signal (NES). Of note, NES of H...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227459/ https://www.ncbi.nlm.nih.gov/pubmed/22145007 http://dx.doi.org/10.1155/2012/426138 |