Titin-Actin Interaction: PEVK-Actin-Based Viscosity in a Large Animal

Titin exhibits an interaction between its PEVK segment and the actin filament resulting in viscosity, a speed dependent resistive force, which significantly influences diastolic filling in mice. While diastolic disease is clinically pervasive, humans express a more compliant titin (N2BA:N2B ratio ~0...

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Detalles Bibliográficos
Autores principales: Chung, Charles S., Bogomolovas, Julius, Gasch, Alexander, Hidalgo, Carlos G., Labeit, Siegfried, Granzier, Henk L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227466/
https://www.ncbi.nlm.nih.gov/pubmed/22162634
http://dx.doi.org/10.1155/2011/310791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227466/
https://www.ncbi.nlm.nih.gov/pubmed/22162634
http://dx.doi.org/10.1155/2011/310791

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