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Activation of Type I Interferon Pathway in Systemic Lupus Erythematosus: Association with Distinct Clinical Phenotypes

Growing evidence over the last few years suggests a central role of type I IFN pathway in the pathogenesis of systemic autoimmune disorders. Data from clinical and genetic studies in patients with systemic lupus erythematosus (SLE) and lupus-prone mouse models, indicates that the type I interferon s...

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Detalles Bibliográficos
Autores principales: Karageorgas, Theophanis P., Tseronis, Dimitrios D., Mavragani, Clio P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227532/
https://www.ncbi.nlm.nih.gov/pubmed/22162633
http://dx.doi.org/10.1155/2011/273907