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Identification of common and cell type specific LXXLL motif EcR cofactors using a bioinformatics refined candidate RNAi screen in Drosophila melanogaster cell lines

BACKGROUND: During Drosophila development, titers of the steroid ecdysone trigger and maintain temporal and tissue specific biological transitions. Decades of evidence reveal that the ecdysone response is both unique to specific tissues and distinct among developmental timepoints. To achieve this di...

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Detalles Bibliográficos
Autores principales: Davis, Melissa B, SanGil, Inigo, Berry, Grace, Olayokun, Rashidat, Neves, Lori H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227616/
https://www.ncbi.nlm.nih.gov/pubmed/22050674
http://dx.doi.org/10.1186/1471-213X-11-66