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GnRH receptor activation competes at a low level with growth signaling in stably transfected human breast cell lines

BACKGROUND: Gonadotrophin releasing hormone (GnRH) analogs lower estrogen levels in pre-menopausal breast cancer patients. GnRH receptor (GnRH-R) activation also directly inhibits the growth of certain cells. The applicability of GnRH anti-proliferation to breast cancer was therefore analyzed. METHO...

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Detalles Bibliográficos
Autores principales: Morgan, Kevin, Meyer, Colette, Miller, Nicola, Sims, Andrew H, Cagnan, Ilgin, Faratian, Dana, Harrison, David J, Millar, Robert P, Langdon, Simon P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227622/
https://www.ncbi.nlm.nih.gov/pubmed/22051164
http://dx.doi.org/10.1186/1471-2407-11-476