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On the Evolutionary Origin of Eukaryotic DNA Methyltransferases and Dnmt2
The Dnmt2 enzymes show strong amino acid sequence similarity with eukaryotic and prokaryotic DNA-(cytosine C5)-methyltransferases. Yet, Dnmt2 enzymes from several species were shown to methylate tRNA-Asp and had been proposed that eukaryotic DNA methyltransferases evolved from a Dnmt2-like tRNA meth...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227630/ https://www.ncbi.nlm.nih.gov/pubmed/22140515 http://dx.doi.org/10.1371/journal.pone.0028104 |