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Heterozygous Yeast Deletion Collection Screens Reveal Essential Targets of Hsp90

Hsp90 is an essential eukaryotic chaperone with a role in folding specific “client” proteins such as kinases and hormone receptors. Previously performed homozygous diploid yeast deletion collection screens uncovered broad requirements for Hsp90 in cellular transport and cell cycle progression. These...

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Detalles Bibliográficos
Autores principales: Franzosa, Eric A., Albanèse, Véronique, Frydman, Judith, Xia, Yu, McClellan, Amie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227642/
https://www.ncbi.nlm.nih.gov/pubmed/22140548
http://dx.doi.org/10.1371/journal.pone.0028211