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Heterozygous Yeast Deletion Collection Screens Reveal Essential Targets of Hsp90
Hsp90 is an essential eukaryotic chaperone with a role in folding specific “client” proteins such as kinases and hormone receptors. Previously performed homozygous diploid yeast deletion collection screens uncovered broad requirements for Hsp90 in cellular transport and cell cycle progression. These...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227642/ https://www.ncbi.nlm.nih.gov/pubmed/22140548 http://dx.doi.org/10.1371/journal.pone.0028211 |