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Spectrum of Oncogenic Driver Mutations in Lung Adenocarcinomas from East Asian Never Smokers
PURPOSE: We previously showed that 90% (47 of 52; 95% CI, 0.79 to 0.96) of lung adenocarcinomas from East Asian never-smokers harbored well-known oncogenic mutations in just four genes: EGFR, HER2, ALK, and KRAS. Here, we sought to extend these findings to more samples and identify driver alteration...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227646/ https://www.ncbi.nlm.nih.gov/pubmed/22140546 http://dx.doi.org/10.1371/journal.pone.0028204 |