Systematic Comparison of Three Methods for Fragmentation of Long-Range PCR Products for Next Generation Sequencing

Next Generation Sequencing (NGS) technologies are gaining importance in the routine clinical diagnostic setting. It is thus desirable to simplify the workflow for high-throughput diagnostics. Fragmentation of DNA is a crucial step for preparation of template libraries and various methods are current...

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Detalles Bibliográficos
Autores principales: Knierim, Ellen, Lucke, Barbara, Schwarz, Jana Marie, Schuelke, Markus, Seelow, Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227650/
https://www.ncbi.nlm.nih.gov/pubmed/22140562
http://dx.doi.org/10.1371/journal.pone.0028240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227650/
https://www.ncbi.nlm.nih.gov/pubmed/22140562
http://dx.doi.org/10.1371/journal.pone.0028240

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