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The therapeutic potential of inhibitors of the signal transducer and activator of transcription 3 for central nervous system malignancies
BACKGROUND: High-grade primary and metastatic central nervous system (CNS) tumors are common, deadly, and refractory to conventional therapy and continue to be therapeutically challenging. A key nodal transcriptional factor, the signal transducer and activator of transcription 3 (STAT3), drives the...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications Pvt Ltd
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228387/ https://www.ncbi.nlm.nih.gov/pubmed/22140648 http://dx.doi.org/10.4103/2152-7806.89886 |