Cargando…
The therapeutic potential of inhibitors of the signal transducer and activator of transcription 3 for central nervous system malignancies
BACKGROUND: High-grade primary and metastatic central nervous system (CNS) tumors are common, deadly, and refractory to conventional therapy and continue to be therapeutically challenging. A key nodal transcriptional factor, the signal transducer and activator of transcription 3 (STAT3), drives the...
Autor principal: | Heimberger, Amy B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications Pvt Ltd
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228387/ https://www.ncbi.nlm.nih.gov/pubmed/22140648 http://dx.doi.org/10.4103/2152-7806.89886 |
Ejemplares similares
-
Modulating Antiangiogenic Resistance by Inhibiting the Signal Transducer and Activator of Transcription 3 Pathway in Glioblastoma
por: de Groot, John, et al.
Publicado: (2012) -
LMD-20. Immune Suppressive Macrophages and Signal Transducer and Activator of Transcription 3 (STAT3) Expression are common in Melanoma Leptomeningeal Disease
por: Najem, Hinda, et al.
Publicado: (2021) -
Physiological functions of endoplasmic reticulum stress transducer OASIS in central nervous system
por: Saito, Atsushi
Publicado: (2013) -
Cell-directed aptamer therapeutic targeting for cancers including those within the central nervous system
por: Wei, Jun, et al.
Publicado: (2022) -
The Role of Signal Transducer and Activator of Transcription 3 (STAT3) and Its Targeted Inhibition in Hematological Malignancies
por: Arora, Loukik, et al.
Publicado: (2018)