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Significance testing in ridge regression for genetic data

BACKGROUND: Technological developments have increased the feasibility of large scale genetic association studies. Densely typed genetic markers are obtained using SNP arrays, next-generation sequencing technologies and imputation. However, SNPs typed using these methods can be highly correlated due...

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Detalles Bibliográficos
Autores principales: Cule, Erika, Vineis, Paolo, De Iorio, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228544/
https://www.ncbi.nlm.nih.gov/pubmed/21929786
http://dx.doi.org/10.1186/1471-2105-12-372