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AlignHUSH: Alignment of HMMs using structure and hydrophobicity information

BACKGROUND: Sensitive remote homology detection and accurate alignments especially in the midnight zone of sequence similarity are needed for better function annotation and structural modeling of proteins. An algorithm, AlignHUSH for HMM-HMM alignment has been developed which is capable of recognizi...

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Detalles Bibliográficos
Autores principales: Krishnadev, Oruganty, Srinivasan, Narayanaswamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228556/
https://www.ncbi.nlm.nih.gov/pubmed/21729312
http://dx.doi.org/10.1186/1471-2105-12-275