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Enhancer-driven chromatin interactions during development promote escape from silencing by a long non-coding RNA
BACKGROUND: Gene regulation in eukaryotes is a complex process entailing the establishment of transcriptionally silent chromatin domains interspersed with regions of active transcription. Imprinted domains consist of clusters of genes, some of which exhibit parent-of-origin dependent monoallelic exp...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228667/ https://www.ncbi.nlm.nih.gov/pubmed/22085535 http://dx.doi.org/10.1186/1756-8935-4-21 |