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Enhancer-driven chromatin interactions during development promote escape from silencing by a long non-coding RNA

BACKGROUND: Gene regulation in eukaryotes is a complex process entailing the establishment of transcriptionally silent chromatin domains interspersed with regions of active transcription. Imprinted domains consist of clusters of genes, some of which exhibit parent-of-origin dependent monoallelic exp...

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Detalles Bibliográficos
Autores principales: Korostowski, Lisa, Raval, Anjali, Breuer, Gillian, Engel, Nora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228667/
https://www.ncbi.nlm.nih.gov/pubmed/22085535
http://dx.doi.org/10.1186/1756-8935-4-21