SOX2-RNAi attenuates S-phase entry and induces RhoA-dependent switch to protease-independent amoeboid migration in human glioma cells

BACKGROUND: SOX2, a high mobility group (HMG)-box containing transcription factor, is a key regulator during development of the nervous system and a persistent marker of neural stem cells. Recent studies suggested a role of SOX2 in tumor progression. In our previous work we detected SOX2 in glioma c...

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Detalles Bibliográficos
Autores principales: Oppel, Felix, Müller, Nadja, Schackert, Gabriele, Hendruschk, Sandy, Martin, Daniel, Geiger, Kathrin D, Temme, Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228695/
https://www.ncbi.nlm.nih.gov/pubmed/22070920
http://dx.doi.org/10.1186/1476-4598-10-137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228695/
https://www.ncbi.nlm.nih.gov/pubmed/22070920
http://dx.doi.org/10.1186/1476-4598-10-137

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