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Increased Intestinal Permeability Correlates with Sigmoid Mucosa alpha-Synuclein Staining and Endotoxin Exposure Markers in Early Parkinson's Disease
Parkinson's disease (PD) is the second most common neurodegenerative disorder of aging. The pathological hallmark of PD is neuronal inclusions termed Lewy bodies whose main component is alpha-synuclein protein. The finding of these Lewy bodies in the intestinal enteric nerves led to the hypothe...
Autores principales: | Forsyth, Christopher B., Shannon, Kathleen M., Kordower, Jeffrey H., Voigt, Robin M., Shaikh, Maliha, Jaglin, Jean A., Estes, Jacob D., Dodiya, Hemraj B., Keshavarzian, Ali |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228722/ https://www.ncbi.nlm.nih.gov/pubmed/22145021 http://dx.doi.org/10.1371/journal.pone.0028032 |
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