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TRESK Background K(+) Channel Is Inhibited by PAR-1/MARK Microtubule Affinity-Regulating Kinases in Xenopus Oocytes

TRESK (TWIK-related spinal cord K(+) channel, KCNK18) is a major background K(+) channel of sensory neurons. Dominant-negative mutation of TRESK is linked to familial migraine. This important two-pore domain K(+) channel is uniquely activated by calcineurin. The calcium/calmodulin-dependent protein...

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Detalles Bibliográficos
Autores principales: Braun, Gabriella, Nemcsics, Balázs, Enyedi, Péter, Czirják, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228728/
https://www.ncbi.nlm.nih.gov/pubmed/22145024
http://dx.doi.org/10.1371/journal.pone.0028119