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Localization of ASV Integrase-DNA Contacts by Site-Directed Crosslinking and their Structural Analysis
BACKGROUND: We applied crosslinking techniques as a first step in preparation of stable avian sarcoma virus (ASV) integrase (IN)-DNA complexes for crystallographic investigations. These results were then compared with the crystal structures of the prototype foamy virus (PFV) intasome and with publis...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228729/ https://www.ncbi.nlm.nih.gov/pubmed/22145019 http://dx.doi.org/10.1371/journal.pone.0027751 |