Transient mTOR Inhibition Facilitates Continuous Growth of Liver Tumors by Modulating the Maintenance of CD133+ Cell Populations

The mammalian target of the rapamycin (mTOR) pathway, which drives cell proliferation, is frequently hyperactivated in a variety of malignancies. Therefore, the inhibition of the mTOR pathway has been considered as an appropriate approach for cancer therapy. In this study, we examined the roles of m...

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Detalles Bibliográficos
Autores principales: Yang, Zhaojuan, Zhang, Li, Ma, Aihui, Liu, Lanlan, Li, Jinjun, Gu, Jianren, Liu, Yongzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228748/
https://www.ncbi.nlm.nih.gov/pubmed/22145042
http://dx.doi.org/10.1371/journal.pone.0028405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228748/
https://www.ncbi.nlm.nih.gov/pubmed/22145042
http://dx.doi.org/10.1371/journal.pone.0028405

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