Human brain endothelial cells endeavor to immunoregulate CD8 T cells via PD-1 ligand expression in multiple sclerosis

BACKGROUND: Multiple sclerosis (MS), an inflammatory disease of the central nervous system (CNS), is characterized by blood-brain barrier (BBB) disruption and massive infiltration of activated immune cells. Engagement of programmed cell death-1 (PD-1) expressed on activated T cells with its ligands...

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Detalles Bibliográficos
Autores principales: Pittet, Camille L, Newcombe, Jia, Prat, Alexandre, Arbour, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228791/
https://www.ncbi.nlm.nih.gov/pubmed/22067141
http://dx.doi.org/10.1186/1742-2094-8-155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228791/
https://www.ncbi.nlm.nih.gov/pubmed/22067141
http://dx.doi.org/10.1186/1742-2094-8-155

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