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A Systematic Screen to Discover and Analyze Apicoplast Proteins Identifies a Conserved and Essential Protein Import Factor

Parasites of the phylum Apicomplexa cause diseases that impact global health and economy. These unicellular eukaryotes possess a relict plastid, the apicoplast, which is an essential organelle and a validated drug target. However, much of its biology remains poorly understood, in particular its elab...

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Detalles Bibliográficos
Autores principales: Sheiner, Lilach, Demerly, Jessica L., Poulsen, Nicole, Beatty, Wandy L., Lucas, Olivier, Behnke, Michael S., White, Michael W., Striepen, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228799/
https://www.ncbi.nlm.nih.gov/pubmed/22144892
http://dx.doi.org/10.1371/journal.ppat.1002392