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A Systematic Screen to Discover and Analyze Apicoplast Proteins Identifies a Conserved and Essential Protein Import Factor
Parasites of the phylum Apicomplexa cause diseases that impact global health and economy. These unicellular eukaryotes possess a relict plastid, the apicoplast, which is an essential organelle and a validated drug target. However, much of its biology remains poorly understood, in particular its elab...
Autores principales: | Sheiner, Lilach, Demerly, Jessica L., Poulsen, Nicole, Beatty, Wandy L., Lucas, Olivier, Behnke, Michael S., White, Michael W., Striepen, Boris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228799/ https://www.ncbi.nlm.nih.gov/pubmed/22144892 http://dx.doi.org/10.1371/journal.ppat.1002392 |
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