A Temporal Role Of Type I Interferon Signaling in CD8(+) T Cell Maturation during Acute West Nile Virus Infection

A genetic absence of the common IFN- α/β signaling receptor (IFNAR) in mice is associated with enhanced viral replication and altered adaptive immune responses. However, analysis of IFNAR(-/-) mice is limited for studying the functions of type I IFN at discrete stages of viral infection. To define t...

Descripción completa

Detalles Bibliográficos
Autores principales: Pinto, Amelia K., Daffis, Stephane, Brien, James D., Gainey, Maria D., Yokoyama, Wayne M., Sheehan, Kathleen C. F., Murphy, Kenneth M., Schreiber, Robert D., Diamond, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228803/
https://www.ncbi.nlm.nih.gov/pubmed/22144897
http://dx.doi.org/10.1371/journal.ppat.1002407

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228803/
https://www.ncbi.nlm.nih.gov/pubmed/22144897
http://dx.doi.org/10.1371/journal.ppat.1002407

Ejemplares similares