Cargando…
A Temporal Role Of Type I Interferon Signaling in CD8(+) T Cell Maturation during Acute West Nile Virus Infection
A genetic absence of the common IFN- α/β signaling receptor (IFNAR) in mice is associated with enhanced viral replication and altered adaptive immune responses. However, analysis of IFNAR(-/-) mice is limited for studying the functions of type I IFN at discrete stages of viral infection. To define t...
Autores principales: | Pinto, Amelia K., Daffis, Stephane, Brien, James D., Gainey, Maria D., Yokoyama, Wayne M., Sheehan, Kathleen C. F., Murphy, Kenneth M., Schreiber, Robert D., Diamond, Michael S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228803/ https://www.ncbi.nlm.nih.gov/pubmed/22144897 http://dx.doi.org/10.1371/journal.ppat.1002407 |
Ejemplares similares
-
Interferon Regulatory Factor-1 (IRF-1) Shapes Both Innate and CD8(+) T Cell Immune Responses against West Nile Virus Infection
por: Brien, James D., et al.
Publicado: (2011) -
Cell-Specific IRF-3 Responses Protect against West Nile Virus Infection by Interferon-Dependent and -Independent Mechanisms
por: Daffis, Stephane, et al.
Publicado: (2007) -
Selective Blockade of Interferon-α and -β Reveals Their Non-Redundant Functions in a Mouse Model of West Nile Virus Infection
por: Sheehan, Kathleen C. F., et al.
Publicado: (2015) -
IPS-1 Is Essential for the Control of West Nile Virus Infection and Immunity
por: Suthar, Mehul S., et al.
Publicado: (2010) -
2′-O Methylation of the Viral mRNA Cap by West Nile Virus Evades Ifit1-Dependent and -Independent Mechanisms of Host Restriction In Vivo
por: Szretter, Kristy J., et al.
Publicado: (2012)