Ringer's lactate improves liver recovery in a murine model of acetaminophen toxicity

BACKGROUND: Acetaminophen (APAP) overdose induces massive hepatocyte necrosis. Liver regeneration is a vital process for survival after a toxic insult. Since hepatocytes are mostly in a quiescent state (G(0)), the regeneration process requires the priming of hepatocytes by cytokines such as TNF-α an...

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Detalles Bibliográficos
Autores principales: Yang, Runkuan, Zhang, Shutian, Kajander, Henri, Zhu, Shengtao, Koskinen, Marja-Leena, Tenhunen, Jyrki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228804/
https://www.ncbi.nlm.nih.gov/pubmed/22085740
http://dx.doi.org/10.1186/1471-230X-11-125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228804/
https://www.ncbi.nlm.nih.gov/pubmed/22085740
http://dx.doi.org/10.1186/1471-230X-11-125

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