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Ringer's lactate improves liver recovery in a murine model of acetaminophen toxicity
BACKGROUND: Acetaminophen (APAP) overdose induces massive hepatocyte necrosis. Liver regeneration is a vital process for survival after a toxic insult. Since hepatocytes are mostly in a quiescent state (G(0)), the regeneration process requires the priming of hepatocytes by cytokines such as TNF-α an...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228804/ https://www.ncbi.nlm.nih.gov/pubmed/22085740 http://dx.doi.org/10.1186/1471-230X-11-125 |