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454 antibody sequencing - error characterization and correction
BACKGROUND: 454 sequencing is currently the method of choice for sequencing of antibody repertoires and libraries containing large numbers (10(6 )to 10(12)) of different molecules with similar frameworks and variable regions which poses significant challenges for identifying sequencing errors. Ident...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228814/ https://www.ncbi.nlm.nih.gov/pubmed/21992227 http://dx.doi.org/10.1186/1756-0500-4-404 |