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454 antibody sequencing - error characterization and correction

BACKGROUND: 454 sequencing is currently the method of choice for sequencing of antibody repertoires and libraries containing large numbers (10(6 )to 10(12)) of different molecules with similar frameworks and variable regions which poses significant challenges for identifying sequencing errors. Ident...

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Detalles Bibliográficos
Autores principales: Prabakaran, Ponraj, Streaker, Emily, Chen, Weizao, Dimitrov, Dimiter S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228814/
https://www.ncbi.nlm.nih.gov/pubmed/21992227
http://dx.doi.org/10.1186/1756-0500-4-404

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