Hierarchical Generalized Linear Models for Multiple Groups of Rare and Common Variants: Jointly Estimating Group and Individual-Variant Effects

Complex diseases and traits are likely influenced by many common and rare genetic variants and environmental factors. Detecting disease susceptibility variants is a challenging task, especially when their frequencies are low and/or their effects are small or moderate. We propose here a comprehensive...

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Detalles Bibliográficos
Autores principales: Yi, Nengjun, Liu, Nianjun, Zhi, Degui, Li, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228815/
https://www.ncbi.nlm.nih.gov/pubmed/22144906
http://dx.doi.org/10.1371/journal.pgen.1002382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228815/
https://www.ncbi.nlm.nih.gov/pubmed/22144906
http://dx.doi.org/10.1371/journal.pgen.1002382

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