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Identification of a Genomic Reservoir for New TRIM Genes in Primate Genomes

Tripartite Motif (TRIM) ubiquitin ligases act in the innate immune response against viruses. One of the best characterized members of this family, TRIM5α, serves as a potent retroviral restriction factor with activity against HIV. Here, we characterize what are likely to be the youngest TRIM genes i...

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Detalles Bibliográficos
Autores principales: Han, Kyudong, Lou, Dianne I., Sawyer, Sara L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228819/
https://www.ncbi.nlm.nih.gov/pubmed/22144910
http://dx.doi.org/10.1371/journal.pgen.1002388