Cargando…

SREBP Coordinates Iron and Ergosterol Homeostasis to Mediate Triazole Drug and Hypoxia Responses in the Human Fungal Pathogen Aspergillus fumigatus

Sterol regulatory element binding proteins (SREBPs) are a class of basic helix-loop-helix transcription factors that regulate diverse cellular responses in eukaryotes. Adding to the recognized importance of SREBPs in human health, SREBPs in the human fungal pathogens Cryptococcus neoformans and Aspe...

Descripción completa

Detalles Bibliográficos
Autores principales: Blatzer, Michael, Barker, Bridget M., Willger, Sven D., Beckmann, Nicola, Blosser, Sara J., Cornish, Elizabeth J., Mazurie, Aurelien, Grahl, Nora, Haas, Hubertus, Cramer, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228822/
https://www.ncbi.nlm.nih.gov/pubmed/22144905
http://dx.doi.org/10.1371/journal.pgen.1002374