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Prediction of RNA Polymerase II recruitment, elongation and stalling from histone modification data

BACKGROUND: Initiation and elongation of RNA polymerase II (RNAPII) transcription is regulated by both DNA sequence and chromatin signals. Recent breakthroughs make it possible to measure the chromatin state and activity of core promoters genome-wide, but dedicated computational strategies are neede...

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Detalles Bibliográficos
Autores principales: Chen, Yun, Jørgensen, Mette, Kolde, Raivo, Zhao, Xiaobei, Parker, Brian, Valen, Eivind, Wen, Jiayu, Sandelin, Albin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228824/
https://www.ncbi.nlm.nih.gov/pubmed/22047616
http://dx.doi.org/10.1186/1471-2164-12-544