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Prediction of RNA Polymerase II recruitment, elongation and stalling from histone modification data
BACKGROUND: Initiation and elongation of RNA polymerase II (RNAPII) transcription is regulated by both DNA sequence and chromatin signals. Recent breakthroughs make it possible to measure the chromatin state and activity of core promoters genome-wide, but dedicated computational strategies are neede...
Autores principales: | Chen, Yun, Jørgensen, Mette, Kolde, Raivo, Zhao, Xiaobei, Parker, Brian, Valen, Eivind, Wen, Jiayu, Sandelin, Albin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228824/ https://www.ncbi.nlm.nih.gov/pubmed/22047616 http://dx.doi.org/10.1186/1471-2164-12-544 |
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