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The Major Roles of DNA Polymerases Epsilon and Delta at the Eukaryotic Replication Fork Are Evolutionarily Conserved

Coordinated replication of eukaryotic genomes is intrinsically asymmetric, with continuous leading strand synthesis preceding discontinuous lagging strand synthesis. Here we provide two types of evidence indicating that, in fission yeast, these two biosynthetic tasks are performed by two different r...

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Detalles Bibliográficos
Autores principales: Miyabe, Izumi, Kunkel, Thomas A., Carr, Antony M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228825/
https://www.ncbi.nlm.nih.gov/pubmed/22144917
http://dx.doi.org/10.1371/journal.pgen.1002407