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Comparing the immunosuppressive potency of naïve marrow stromal cells and Notch-transfected marrow stromal cells

BACKGROUND: SB623 cells are expanded from marrow stromal cells (MSCs) transfected with a Notch intracellular domain (NICD)-expressing plasmid. In stroke-induced animals, these cells reduce infarct size and promote functional recovery. SB623 cells resemble the parental MSCs with respect to morphology...

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Detalles Bibliográficos
Autores principales: Dao, Mo A, Tate, Ciara C, Aizman, Irina, McGrogan, Michael, Case, Casey C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228829/
https://www.ncbi.nlm.nih.gov/pubmed/21982515
http://dx.doi.org/10.1186/1742-2094-8-133