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Mitochondrial NAD(+)-dependent malic enzyme from Anopheles stephensi: a possible novel target for malaria mosquito control

BACKGROUND: Anopheles stephensi mitochondrial malic enzyme (ME) emerged as having a relevant role in the provision of pyruvate for the Krebs' cycle because inhibition of this enzyme results in the complete abrogation of oxygen uptake by mitochondria. Therefore, the identification of ME in mitoc...

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Detalles Bibliográficos
Autores principales: Pon, Jennifer, Napoli, Eleonora, Luckhart, Shirley, Giulivi, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228860/
https://www.ncbi.nlm.nih.gov/pubmed/22029897
http://dx.doi.org/10.1186/1475-2875-10-318