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A role for caveolin-1 in desmoglein binding and desmosome dynamics

Desmoglein 2 (Dsg2) is a desmosomal cadherin that is aberrantly expressed in human skin carcinomas. In addition to its well-known role in mediating intercellular desmosomal adhesion, Dsg2 regulates mitogenic signaling that may promote cancer development and progression. However, the mechanisms by wh...

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Detalles Bibliográficos
Autores principales: Brennan, Donna, Peltonen, Sirkku, Dowling, Alicia, Medhat, Walid, Green, Kathleen J., Wahl, James K., Del Galdo, Francesco, Mahoney, Mỹ G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228894/
https://www.ncbi.nlm.nih.gov/pubmed/21841821
http://dx.doi.org/10.1038/onc.2011.346