Extracellular loops 1 and 3 and their associated transmembrane regions of the calcitonin receptor-like receptor are needed for CGRP receptor function

The first and third extracellular loops (ECL) of G protein-coupled receptors (GPCRs) have been implicated in ligand binding and receptor function. This study describes the results of an alanine/leucine scan of ECLs 1 and 3 and loop-associated transmembrane (TM) domains of the secretin-like GPCR calc...

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Detalles Bibliográficos
Autores principales: Barwell, James, Conner, Alex, Poyner, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228915/
https://www.ncbi.nlm.nih.gov/pubmed/21703310
http://dx.doi.org/10.1016/j.bbamcr.2011.06.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228915/
https://www.ncbi.nlm.nih.gov/pubmed/21703310
http://dx.doi.org/10.1016/j.bbamcr.2011.06.005

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