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Drug Discovery Toward Antagonists of Methyl-Lysine Binding Proteins

The recognition of methyl-lysine and -arginine residues on both histone and other proteins by specific “reader” elements is important for chromatin regulation, gene expression, and control of cell-cycle progression. Recently the crucial role of these reader proteins in cancer development and dediffe...

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Detalles Bibliográficos
Autores principales: Herold, J. Martin, Ingerman, Lindsey A, Gao, Cen, Frye, Stephen V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229088/
https://www.ncbi.nlm.nih.gov/pubmed/22145013
http://dx.doi.org/10.2174/1875397301005010051