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A Computational Investigation of Cardiac Caveolae as a Source of Persistent Sodium Current
Recent studies of cholesterol-rich membrane microdomains, called caveolae, reveal that caveolae are reservoirs of “recruitable” sodium ion channels. Caveolar channels constitute a substantial and previously unrecognized source of sodium current in cardiac cells. In this paper we model for the first...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229093/ https://www.ncbi.nlm.nih.gov/pubmed/22144962 http://dx.doi.org/10.3389/fphys.2011.00087 |